These ASX shares could rise 20% to 60%

Analysts see major upside potential for these stocks.

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Are you hunting big returns for your investment portfolio? Of course you are! Who isn't?

Well, I have some good news for you.

The three ASX shares that are listed below have been tipped to rise 20% to 60% from current levels. This is significantly greater than the historical average annual market return of 10%.

Here's what analysts are tipping from these ASX shares:

Neuren Pharmaceuticals Ltd (ASX: NEU)

Analysts at Bell Potter think huge returns could be on the cards for buyers of this pharmaceuticals company's shares.

Last week, its analysts retained their buy rating and $25.00 price target on the ASX share. Based on its current share price of $15.57, this suggests that upside of 60% is possible for investors.

Bell Potter remains very positive on the company due to its NNZ-2591 product candidate.

Its analysts advised that they "continue to view NNZ-2591 as a valuable asset that is likely to start one, if not two, Phase 3 trials in CY25 in attractive orphan indications. We maintain our $25/share PT of which ~$10/share is attributed to Daybue licensing income."

Origin Energy Ltd (ASX: ORG)

Another ASX share that could generate big returns is energy giant Origin Energy.

In response to its full year results last week, analysts at UBS retained their buy rating on the company's shares with a slightly trimmed price target of $11.70.

Based on its current share price of $9.66, this implies potential upside of 21% for investors over the next 12 months. In addition, a dividend yield greater than 5% is expected in FY 2025, which boosts the total return further.

Rio Tinto Ltd (ASX: RIO)

Finally, Goldman Sachs thinks that this mining giant could generate big returns for investors over the next 12 months.

The broker currently has a buy rating and $136.60 price target on Rio Tinto's shares. This implies potential upside of 24% for investors between now and this time next year. In addition, Goldman is forecasting a 6% dividend yield over the period, which stretches the total potential return to 30%.

Its analysts highlight that "RIO is a FCF and production growth story in our view, with forecast Cu Eq production growth of ~4-7% in 2025 & 2026 driven mostly by the ramp-up of the Oyu Tolgoi UG copper mine & a recovery at Escondida and Bingham, higher Pilbara Fe shipments with the ramp-up of new mines, and a rebound in aluminium production."

Motley Fool contributor James Mickleboro has no position in any of the stocks mentioned. The Motley Fool Australia's parent company Motley Fool Holdings Inc. has positions in and has recommended Goldman Sachs Group. The Motley Fool Australia has no position in any of the stocks mentioned. The Motley Fool has a disclosure policy. This article contains general investment advice only (under AFSL 400691). Authorised by Scott Phillips.

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