Which ASX 300 shares are making the biggest moves on Tuesday?

The ASX 300 is spending the day in the red…

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The S&P/ASX 300 Index (ASX: XKO) is in reverse in afternoon trade today. At the time of writing, the ASX 300 is down 0.32% to 7,508 points.

Let's take a look at which ASX companies are leading the charge today.

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Image source: Getty Images

Flight Centre Travel Group Ltd (ASX: FLT)

The Flight Centre share price accelerated 6% to a 5-month high of $18.55 in morning trade. At the time of writing it has fallen slightly to $18.40, still a gain of 5.14%.

The rise comes despite no news out of the travel agent since its positive market release last week.

A possible catalyst for the strong rise in the company's shares could be Australia's accelerated vaccination program.

Current estimates indicate that in a little over two months, Australia will have 70% of its citizens fully vaccinated. This will allow state governments to relax harsh restrictions, and reopen the economy.

Imugene Limited (ASX: IMU)

The Imugene share price is surging by 5.50% to 42 cents despite no news coming from the clinical-stage immuno-oncology company.

It appears investors are taking advantage of Imugene shares, following the inclusion to the ASX Index. This is set to occur officially prior to the market open on September 20.

Chalice Mining Ltd (ASX: CHN)

Another big mover on the ASX 300 is the Chalice share price, up 5.48% to $7.32.

The gold explorer has been on the move this week due to the rising spot price of gold. Demand for the yellow metal has soared since 2 September to hit US$1,826 per ounce.

And the biggest fallers for the day?

Johns Lyng Group Ltd (ASX: JLG)

The worst performer on the ASX 300 today is the Johns Lyng share price, down 5.53% to $5.81.

After the building services group's shares gained almost 12% since 27 August, some investors have taken profit off the table.

Over the past 12 months, Johns Lyng shares are up more than 120%, and more than 80% year to date.

Centuria Office REIT (ASX: COF)

Lastly, the Centuria Office REIT share price is also heading lower on Tuesday, declining 5.21% to $2.455.

The property company announced the successful completion of its institutional entitlement offer, raising $129 million.

A further $72 million is expected to be raised in a retail entitlement offer, opening next Monday to eligible shareholders.

Motley Fool contributor Aaron Teboneras has no position in any of the stocks mentioned. The Motley Fool Australia's parent company Motley Fool Holdings Inc. has no position in any of the stocks mentioned. The Motley Fool Australia has recommended Flight Centre Travel Group Limited. The Motley Fool has a disclosure policy. This article contains general investment advice only (under AFSL 400691). Authorised by Bruce Jackson.

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